OPEN CALLS FOR FUNDING
GLACIER team meeting in Costa Rica to close the first funding phase
GLACIER’s team met in Costa Rica to close the first funding phase (2020–2025) and launch the roadmap for GLACIER 2...
Exploration of the Tertiary Amide Chemical Space of Dolastatin 15 Analogs Reveals New Insights into the Structure–Anticancer Activity Relationship
Dolastatins are a class of naturally occurring antimitotic peptides that have inspired the development of some of the...
Viral Symmetries
Viral Symmetries is a bioart exhibition that transforms the invisible world of viruses into a visual and sensory...
Pore-forming peptide C14R exhibits potent antifungal activity against clinical isolates of Candida albicans and Candida auris
Introduction: Invasive candidiasis is a global public health problem as it poses a significant threat in...
Multicomponent Functionalization of the Octreotide Peptide Macrocyclic Scaffold
The replacement of the disulfide bridge by other types of side chain linkages has been a continuous endeavor in the...
Effect of O-Acetylation on the Antigenicity and Glycoconjugate Immunogenicity of the Streptococcus Pneumoniae Serotype 7F Capsular Polysaccharide
Streptococcus pneumoniae is a bacterial pathogen causing diseases as severe as pneumonia, sepsis and meningitis. Most...
Epidemiological, virological and clinical characterization of a Dengue/Zika outbreak in the Caribbean region of Costa Rica 2017–2018
The increase in incidence and geographical expansion of viruses transmitted by the Aedes mosquitoes, such as dengue...
A COVID-19 vaccine candidate composed of the SARS-CoV-2 RBD dimer and Neisseria meningitidis outer membrane vesicles
SARS-CoV-2 infection is mediated by the interaction of the spike glycoprotein trimer via its receptor-binding domain...
In vitro Characterization of Anti-SARS-CoV-2 Intravenous Immunoglobulins (IVIg) Produced From Plasma of Donors Immunized With the BNT162b2 Vaccine and Its Comparison With a Similar Formulation Produced From Plasma of COVID-19 Convalescent Donors
Despite vaccines are the main strategy to control the ongoing global COVID-19 pandemic, their effectiveness could not...
Improved Access to Potent Anticancer Tubulysins and Linker-Functionalized Payloads Via an All-On-Resin Strategy
Tubulysins are among the most recent antimitotic compounds to enter into antibody/peptide-drug conjugate (ADC/PDC)...
Serologic Evidence for Early SARS–CoV-2 Circulation in Lima, Peru, 2020
During early 2021, Peru had the highest COVID-19–associated per-capita mortality rate. Socioeconomic inequality,...
The Designed Pore-Forming Antimicrobial Peptide C14R Combines Excellent Activity against the Major Opportunistic Human Pathogen Pseudomonas aeruginosa with Low Cytotoxicity
The diminishing portfolio of mankind’s available antibiotics urges science to develop novel potent drugs. Here, we...
GLACIER team meeting in Costa Rica to close the first funding phase
GLACIER’s team met in Costa Rica to close the first funding phase (2020–2025) and launch the roadmap for GLACIER 2...
Exploration of the Tertiary Amide Chemical Space of Dolastatin 15 Analogs Reveals New Insights into the Structure–Anticancer Activity Relationship
Dolastatins are a class of naturally occurring antimitotic peptides that have inspired the development of some of the...
Viral Symmetries
Viral Symmetries is a bioart exhibition that transforms the invisible world of viruses into a visual and sensory...
Pore-forming peptide C14R exhibits potent antifungal activity against clinical isolates of Candida albicans and Candida auris
Introduction: Invasive candidiasis is a global public health problem as it poses a significant threat in...
Multicomponent Functionalization of the Octreotide Peptide Macrocyclic Scaffold
The replacement of the disulfide bridge by other types of side chain linkages has been a continuous endeavor in the...
Effect of O-Acetylation on the Antigenicity and Glycoconjugate Immunogenicity of the Streptococcus Pneumoniae Serotype 7F Capsular Polysaccharide
Streptococcus pneumoniae is a bacterial pathogen causing diseases as severe as pneumonia, sepsis and meningitis. Most...
Epidemiological, virological and clinical characterization of a Dengue/Zika outbreak in the Caribbean region of Costa Rica 2017–2018
The increase in incidence and geographical expansion of viruses transmitted by the Aedes mosquitoes, such as dengue...
A COVID-19 vaccine candidate composed of the SARS-CoV-2 RBD dimer and Neisseria meningitidis outer membrane vesicles
SARS-CoV-2 infection is mediated by the interaction of the spike glycoprotein trimer via its receptor-binding domain...
In vitro Characterization of Anti-SARS-CoV-2 Intravenous Immunoglobulins (IVIg) Produced From Plasma of Donors Immunized With the BNT162b2 Vaccine and Its Comparison With a Similar Formulation Produced From Plasma of COVID-19 Convalescent Donors
Despite vaccines are the main strategy to control the ongoing global COVID-19 pandemic, their effectiveness could not...
Improved Access to Potent Anticancer Tubulysins and Linker-Functionalized Payloads Via an All-On-Resin Strategy
Tubulysins are among the most recent antimitotic compounds to enter into antibody/peptide-drug conjugate (ADC/PDC)...
Serologic Evidence for Early SARS–CoV-2 Circulation in Lima, Peru, 2020
During early 2021, Peru had the highest COVID-19–associated per-capita mortality rate. Socioeconomic inequality,...
The Designed Pore-Forming Antimicrobial Peptide C14R Combines Excellent Activity against the Major Opportunistic Human Pathogen Pseudomonas aeruginosa with Low Cytotoxicity
The diminishing portfolio of mankind’s available antibiotics urges science to develop novel potent drugs. Here, we...