SCIENTIFIC PUBLICATIONS
Synthesis and Evaluation of Peptoid-Based Compound Libraries as Inhibitors of Parasite Metallo-Aminopeptidases
Parasitic diseases are a worldwide health and socio-economical problem, especially due to increasing parasite...
Creating unimolecular multivalent diversity in protein conjugates via the Passerini multicomponent bioconjugation with isocyanoproteins
The ability to conjugate multiple molecules to a protein is of great interest for pharmaceutical and vaccine...
Impact of C-Terminal Amide N-Derivatization on the Conformational Dynamics and Antimitotic Activity of Cemadotin Analogues
Tubulin is a heterodimeric protein composed of α- and β-subunits, which polymerize to form the cell’s microtubules....
Exploration of the Tertiary Amide Chemical Space of Dolastatin 15 Analogs Reveals New Insights into the Structure–Anticancer Activity Relationship
Dolastatins are a class of naturally occurring antimitotic peptides that have inspired the development of some of the...
Pore-forming peptide C14R exhibits potent antifungal activity against clinical isolates of Candida albicans and Candida auris
Introduction: Invasive candidiasis is a global public health problem as it poses a significant threat in...
Multicomponent Functionalization of the Octreotide Peptide Macrocyclic Scaffold
The replacement of the disulfide bridge by other types of side chain linkages has been a continuous endeavor in the...
Seroprevalence of Oropouche virus following the 2024–2025 outbreak in Cuba
Since 2024, Cuba has suffered concurrent outbreaks of arboviruses, including Oropouche virus (OROV) and dengue virus....
Scientific mobility in microbiology: Andres Moreira Soto in Trends in Microbiology
In a recent Trends in Microbiology TrendsTalk, Dr. Andres Moreira Soto reflects on how scientific mobility shaped his...
Epidemiological, virological and clinical characterization of a Dengue/Zika outbreak in the Caribbean region of Costa Rica 2017–2018
The increase in incidence and geographical expansion of viruses transmitted by the Aedes mosquitoes, such as dengue...
Ancient evolutionary origins of hepatitis E virus in rodents
Hepatitis E virus (HEV; family Hepeviridae) infections cause >40,000 human deaths annually. Zoonotic infections...
Discovery and biological confirmation of a highly divergent Tacaribe virus in metatranscriptomic data from neotropical bats
First isolated from neotropical fruit bats in Trinidad in 1956, Tacaribe virus (TCRV) has rarely been detected since....
Socioeconomic determinants potentially underlying differential global SARS-CoV-2 testing capacity: an ecological study
This study, conducted by Dr. Andrés Moreira-Soto, Dr. Jan Felix Drexler (Charité - Universitätsmedizin Berlin) and...
Effect of O-Acetylation on the Antigenicity and Glycoconjugate Immunogenicity of the Streptococcus Pneumoniae Serotype 7F Capsular Polysaccharide
Streptococcus pneumoniae is a bacterial pathogen causing diseases as severe as pneumonia, sepsis and meningitis. Most...
A COVID-19 vaccine candidate composed of the SARS-CoV-2 RBD dimer and Neisseria meningitidis outer membrane vesicles
SARS-CoV-2 infection is mediated by the interaction of the spike glycoprotein trimer via its receptor-binding domain...
In vitro Characterization of Anti-SARS-CoV-2 Intravenous Immunoglobulins (IVIg) Produced From Plasma of Donors Immunized With the BNT162b2 Vaccine and Its Comparison With a Similar Formulation Produced From Plasma of COVID-19 Convalescent Donors
Despite vaccines are the main strategy to control the ongoing global COVID-19 pandemic, their effectiveness could not...
Serologic Evidence for Early SARS–CoV-2 Circulation in Lima, Peru, 2020
During early 2021, Peru had the highest COVID-19–associated per-capita mortality rate. Socioeconomic inequality,...
Link of TMPRSS2 expression with tumor immunogenicity and response to immune checkpoint inhibitors in cancers
In this article, Subbarayan et al. analyze the role of the TMPRSS2 protein, which helps SARS-CoV-2 enter cells, in...
One Health in Mesoamerica: historical legacies, current challenges, and strategic directions
Mesoamerica, a biodiversity hotspot extending from Mexico to Panama, faces intersecting health challenges rooted in...
In a Stranglehold
In a recent commentary, Bert Hoffmann argues that Cuba is entering a critical phase as U.S. policy increasingly...
Prof. Dr. Bert Hoffmann outlines major trends shaping Latin America in 2026
A new policy brief from GIGA by Bert Hoffmann, a member of the GLACIER Steering Committee, offers a forward-looking...
Gemeinsam gegen Pandemien (Working together against pandemics)
The aim is to improve the research infrastructure in Latin America, with a particular focus on producing...
After the protests and the pandemic: reassessing the international profile of Post-Castro Cuba
As Cuba enters 2022, economic crisis and social tensions loom large. The paper reviews the external difficulties that...
Synthesis and Evaluation of Peptoid-Based Compound Libraries as Inhibitors of Parasite Metallo-Aminopeptidases
Parasitic diseases are a worldwide health and socio-economical problem, especially due to increasing parasite...
Creating unimolecular multivalent diversity in protein conjugates via the Passerini multicomponent bioconjugation with isocyanoproteins
The ability to conjugate multiple molecules to a protein is of great interest for pharmaceutical and vaccine...
Impact of C-Terminal Amide N-Derivatization on the Conformational Dynamics and Antimitotic Activity of Cemadotin Analogues
Tubulin is a heterodimeric protein composed of α- and β-subunits, which polymerize to form the cell’s microtubules....
Seroprevalence of Oropouche virus following the 2024–2025 outbreak in Cuba
Since 2024, Cuba has suffered concurrent outbreaks of arboviruses, including Oropouche virus (OROV) and dengue virus....
One Health in Mesoamerica: historical legacies, current challenges, and strategic directions
Mesoamerica, a biodiversity hotspot extending from Mexico to Panama, faces intersecting health challenges rooted in...
Scientific mobility in microbiology: Andres Moreira Soto in Trends in Microbiology
In a recent Trends in Microbiology TrendsTalk, Dr. Andres Moreira Soto reflects on how scientific mobility shaped his...